2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT

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专利权人:

GILEAD SCIENCES INC

发明人:

CHO AESOP,KIM CHOUNG,RAY ADRIAN

申请号：

AP2013006767

公开号：

AP3699A

申请日:

2011.03.22

申请国别(地区):

AP

年份:

2016

代理人:

摘要：

Provided are select imidazo[1,2-f][1,2,4] triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 2' position of the nucleoside sugar is substituted with halogen and carbon substituents. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections caused by both wild type and mutant strains of HCV. Formula (I)

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