LEE, SAET BYOULKR,이샛별,SHIN, DONG KYUKR,신동규,KIM, KYUNG AHKR,김경아,LEE, JI MINKR,이지민
申请号:
KR1020140175232
公开号:
KR1020160069363A
申请日:
2014.12.08
申请国别(地区):
KR
年份:
2016
代理人:
摘要:
Provided are: a method for selecting an antibody, comprising a step of measuring a level and/or a binding state of antigen-antibody in various pH and an antibody-drug conjugate comprising the selected antibody. The method for selecting an antibody of the present invention can be applied to the development of an antibody which can effectively degrade an antigen. In addition, the selected antibody is useful as an antibody for treatment.COPYRIGHT KIPO 2016다양한 pH에서의 항원-항체 결합 여부 및/또는 수준을 측정하는 단계를 포함하는 항체 선별 방법, 및 상기 선별된 항체를 포함하는 항체-약물 접합체 (Antibody-Drug Conjugate)를 제공한다.