JAMES H. ADAIR,SEAN D. KNECHT,J. ERIC BOYER,RICHARD L. TUTWILER,CONNOR CARR,XIAOMENG TANG,BERNADETTE M. ADAIR,THOMAS NEUBERGER,WELLEY S. LOC,ZACHARY R. WILCZYNSKI,CHRISTOPHER MCGOVERN,GAIL L. MATTERS
申请号:
US15699215
公开号:
US20180064347A1
申请日:
2017.09.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Systems comprising a combination of the handheld imaging system with a nanoparticle multimodal contrast agent are disclosed. The imaging system exploits the advantages of both near-infrared emission and the photoacoustic effect by employing calcium phosphosilicate nanocolloid that encapsulates NIR and CT/MRI contrast agents for enhanced deep tissue imaging as well as a portable NIR/PA system using a tunable pulsed laser, CCD imaging technology and acoustic transducer arrays. Methods for using the system, for example in rapid diagnosis of trauma such as that inflicted on a battlefield, are provided.