Allan BRADLEY,E-Chiang LEE,Qi LIANG,Wei WANG,Dominik SPENSBERGER,Hui LIU,Jasper CLUBE
申请号:
US15369595
公开号:
US20170081423A1
申请日:
2016.12.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.