The present invention relates to: a pharmaceutical composition for improving drug administration in order to treat fungal infectious diseases of ketratin tissue a preparation method therefor and an administration method therefor. Specifically, the present invention relates to: a pharmaceutical composition for preventing and treating fungal infectious diseases by increasing absorption into ketratin tissue due to containing a) at least one antifungal active material b) an alkalinizing agent capable of maintaining the pH of the composition at pH 7 to pH 13 and c) an organic solvent which dissolves or promotes absorption of the antifungal active material a preparation method therefor and an administration method therefor.La présente invention concerne : une composition pharmaceutique pour améliorer ladministration de médicament de façon à traiter des maladies infectieuses fongiques de tissu de kératine son procédé de préparation et son procédé dadministration. Spécifiquement, la présente invention concerne : une composition pharmaceutique pour prévenir et traiter des maladies infectieuses fongiques par augmentation dabsorption dans un tissu de kératine, car elle contient a) au moins une matière active antifongique b) un agent dalcalinisation capable de maintenir le pH de la composition entre 7 et 13 et c) un solvant organique qui se dissout ou favorise labsorption de la matière active antifongique son procédé de préparation et son procédé dadministration.본 발명은 케라틴조직의 진균감염증 치료를 위해 약물투과를 향상시키는 약제학적 조성물, 제조방법 및 그 투여방법에 관한 것으로서, 구체적으로는 a) 적어도 하나 이상의 항진균성 활성물질 b) pH 7 ~ pH 13으로 할 수 있는 알칼리화제 및 c) 항진균 활성성분을 용해하거나 흡수를 촉진하는 유기용매를 함유하여 케라틴 조직의 흡수를 증가시켜 진균감염증을 예방 및 치료하기 위한 약제학적 조성물, 제조방법 및 투여방법에 관한 것이다.