Disclosed are methylpyrrolopyrimidinecarboxamide compounds of formula (I), salts thereof, and methods for their preparation. Specific examples of compounds of formula (I) include: N-(1-Acetylpiperidin-4-yl)-4-[5-(cyclopropylmethoxy)-1,3-benzodioxol-4-yl]-6-methyl-5H-pyrrolo[3,2-5d]pyrimidine-7-carboxamide, 4-[2-(Cyclopropylmethoxy)-5-fluorophenyl]-N-[(3R)-1-(methoxyacetyl)pyrrolidin-3-yl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxamide, N-[(3R)-1-acetylpyrrolidin-3-yl]-4-[2-(cyclopropylmethoxy)-5-methoxyphenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxamide, and 4-[2-(Cyclopropylmethoxy)-4-fluoro-5-methylphenyl]-N-{ trans-4-[(methoxyacetyl)amino]cyclohexyl} -6-methyl-5H-pyrrolo[3,2 -d]pyrimidine-7-carboxamide. Compounds of formula (I) are useful for the treatment or prophylaxis of an acute or chronic airway disease, hypertension, nephritis, liver cirrhosis, toxic liver damage, hepatitis, non-alcoholic steatohepatitis or liver fibrosis.
