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METASTIN DERIVATIVES AND USE THEREOF
专利权人:
TAKEDA PHARMACEUTICAL COMPANY LIMITED
发明人:
ASAMI TAIJI,ASAMI Taiji,NISHIZAWA NAOKI,NISHIZAWA Naoki
申请号:
SI200731649
公开号:
SI2081955T1
申请日:
2007.10.24
申请国别(地区):
SI
年份:
2015
代理人:
摘要:
The present invention provides stable metastin derivatives having excellent biological activities (a cancer metastasis suppressing activity, a cancer growth suppressing activity, a gonadotropic hormone secretion stimulating activity, sex hormone secretion stimulating activity, etc.). By substituting the constituent amino acids of metastin with specific amino acids, the metastin derivatives of the present invention achieve more improved blood stability, solubility, etc., reduced gelation tendency, improved pharmacokinetics, as well as exhibit an excellent cancer metastasis suppressing activity or a cancer growth suppressing activity. The metastin derivatives of the present invention also have a gonadotropic hormone secretion suppressing activity, sex hormone secretion suppressing activity, etc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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