The United States of America; as represented by the Secretary; Dept. of Health and Human Services
发明人:
Rong-Fu Wang,Steven A. Rosenberg,Gang Zeng
申请号：
US14284971
公开号：
US20140335053A1
申请日:
2014.05.22
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention discloses the identification and isolation of novel MHC class II epitopes derived from the cancer antigen, NY ESO-1. The novel MHC class II epitopes from NY-EsO-1 are recognized by CD4+ T lymphocytes in an HLA class II restricted manner, in particular HLA-DR or HLA-DP restricted. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer.
