PROBLEM TO BE SOLVED: To provide a dermofluorometer capable of accurately measuring fluorescence from a skin surface after removing an impact of a pigment such as melanin as much as possible, thereby estimating an amount of AGEs correctly.SOLUTION: A dermofluorometer includes: a measuring head 2 that is brought into contact with a skin 1 which is a measurement object, and irradiates light toward a skin surface and an operation box 6 having a control circuit 3 that estimates an amount of an advanced glycation end product of the skin based on the information on light volume measured by the measuring head 2. The measuring head 2 includes an ultraviolet emitting element 11uv, and red, green, and blue light emitting elements 11r, 11g, and 11b, each emitting the light at different time zones. An amount of melanin is calculated based on the information on an amount of light reflected from the skin 1 when the light is irradiated from each of the light emitting elements 11r, 11g, and 11b, and a value of absorbance according to the calculated amount of melanin is added to an amount of fluorescence at the time when the ultraviolet emitting element 11uv irradiates the ultraviolet light so as to obtain a corrected amount of fluorescence.SELECTED DRAWING: Figure 3COPYRIGHT: (C)2016,JPO&INPIT【課題】皮膚表面からの蛍光を、メラニンなどの色素の影響を可能な限り除外した上で正確に測定することができ、ひいてはAGEsの量を正しく推定する。【解決手段】測定対象である皮膚1に当接されて皮膚表面に向けて光を照射する測定ヘッド2と、測定ヘッド2が測定した光量情報に基づいて皮膚の最終糖化産物の量を推定する制御回路3を有した操作ボックス6を備える。測定ヘッド2は、各々異なる時間帯に発光する紫外光発光素子11uv及び赤、緑、青色光発光素子11r、11g、11bを備え、各発光素子11r、11g、11bが光を照射したときの皮膚1からの反射光量についての情報に基づいてメラニンの量を算出し、算出したメラニンの量に応じた吸収度の値を、紫外光発光素子11uvが紫外光を照射したときの蛍光量に加算して補正蛍光量とする。【選択図】図3
