Gerhard Winter;Wolfgang Fraunhofer;Stefan Gottschalk;David W. Borhani
发明人:
Wolfgang Fraunhofer,David W. Borhani,Gerhard Winter,Stefan Gottschalk
申请号：
US12228038
公开号：
US08753839B2
申请日:
2008.08.08
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a batch crystallization method for crystallizing anti-human TNFalpha (hTNFalpha) antibody and antibody fragments which allows the production of said antibody on an industrial scale； a method of controlling the size of antibody crystals, for example, crystals of anti-hTNFalpha antibody fragments, compositions containing said crystals as well as methods of use of said crystals and compositions.
