The invention relates to a powder inhaler and to a powder inhaler set that contains the powder inhaler. The powder inhaler comprises two half-shells (3, 4), which can be or are articulated to each other and which enclose an air inlet region, a powder deposition region and powder release region, and an outlet region in a joined arrangement, through which regions a fluid path extends. At least one of the half shells (3, 4) has at least one air inlet opening (8) in the air inlet region, and at least one air-swirling structure (5) is present in the air inlet region, which air-swirling structure defines the fluid path between the at least one air inlet opening (8) and the powder deposition and release region. Furthermore, one of the half-shells (3, 4) has at least one powder-accommodating recess (9) in the powder deposition region and powder release region, while the outlet region has at least one deagglomeration structure (17, 17′) and an outlet for aerosol, which outlet is formed by the half-shells (3, 4).