Siyuan Tan;Philip D. Gregory;Jeffrey C. Miller;Fyodor Urnov;David Paschon;Lei Zhang;Edward J. Rebar
发明人:
Philip D. Gregory,Jeffrey C. Miller,David Paschon,Edward J. Rebar,Siyuan Tan,Fyodor Urnov,Lei Zhang
申请号：
US13068735
公开号：
US08586526B2
申请日:
2011.05.17
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.
