The present invention relates to a driving method of a laser irradiating system. An example of the driving method of laser irradiating system comprises: a step of determining a status of coolant by decoding a detecting signal which detects the status of the coolant which cools down a flash lamp of the laser irradiating system; a step of notifying an abnormal status of the coolant by outputting a warning signal from a warning part in case the status of the coolant is abnormal; a step of determining a laser irradiating number in case the status of the coolant is normal; a step of notifying a soon expired status of the laser irradiating system by outputting the warning signal from the warning part in case the laser irradiating number is more than predetermined value; a step of determining a laser irradiating part which is selected from a user among multiple laser irradiating parts which output lasers of each different wavelength by decoding a signal which is approved from a laser kind selecting part; a step of adjusting the temperature of the coolant according to the predetermined temperature of the determined laser irradiating part; a step of determining an operation of a laser outputting switch by decoding a signal which is approved from the laser outputting switch; a step of outputting an operating signal which operates the laser irradiating part which is selected by the user to a selected laser irradiating part in case the laser outputting switch is operated. [Reference numerals] (10) A first laser irradiating part; (20) A second laser irradiating part; (30) A cooling unit; (41) A water circulation detecting unit; (42) A water lever detecting unit; (43) A flow velocity detecting unit; (44) A temperature detecting unit; (45) A laser kind selecting part; (46) A laser outputting switch; (50) A control unit; (51) A counter; (52) A storage unit; (60) An alarming part; (70) A first coolant controlling part; (80) A second coolant controlling part본 발명은 레이저 발사 시스템의 구동 방법에 관