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Pharmaceutical suspension aerosol formulations for use in metered dose inhalers
专利权人:
JAGOTEC AG
发明人:
FUEG LISE-MARIE,MUELLER-WALZ RUDI
申请号:
NZ59990010
公开号:
NZ599900A
申请日:
2010.10.15
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is a method to reduce deposition of particles at initial in a metered dose inhaler comprising a canister and metering valve, containing a suspension aerosol formulation comprising particles of formoterol fumarate dihydrate and fluticasone propionate suspended in an HF A propellant, the method reducing deposition of particles on the surfaces of the canister and the metering valve, and the method comprising the step of adding a wetting agent to the formulation, wherein the wetting agent is selected from the group consisting of ethanol, diols or polyols, such as propylene glycol, glycerol, butandiol and mixtures thereof.
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