The present Invention relates to compositions, uses thereof and Methods for vaccinating Cattle, particularly Cows and heifers, against Leptospira borgpetersenii serovar Hardjo (type hardjo bovis) using Leptospira interrogans serovar Hardjo (type Hardjoprajitno).La presente invención se refiere a composiciones, a usos de las mismas y a métodos para vacunar ganado vacuno, particularmente vacas y terneras, contra Leptospira borgpetersenii serovariedad hardjo (tipo hardjo-bovis) usando Leptospira interrogans serovariedad hardjo (tipo hardjoprajitno).