The present teachings provide a device and method of making and using thereof. Specifically, one aspect of the present teachings provides a device comprising a shunt having a distal end and a proximal end and the shunt positionable across the septum of a heart. Certain embodiments of the present teachings also include a distal anchoring portion connecting to the distal end of the shunt portion and a proximal anchoring portion connecting to the proximal end of the shunt portion. Another aspect of the present teachings provide methods of using thereof to modify the pressure difference in a heart chamber.