PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
发明人:
HA, KI TAEKR,하기태,CHOI, HEE JUNGKR,최희정,CHUNG, TAE WOOKKR,정태욱
申请号：
KR1020150056700
公开号：
KR1020160125781A
申请日:
2015.04.22
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a composition for preventing or treating sterility or infertility comprising a sialylated Tn antigenic carbohydrate, or an activation agent of the antigen as an active component. Further, the present invention relates to a pharmaceutical composition for contraception comprising an inhibitor of a sialylated Tn antigenic carbohydrate, or an expression or active inhibitor of enzymes which synthesize the antigen. Further, the present invention relates to a marker composition for measuring pregnancy possibility or pregnancy efficiency comprising a sialylated Tn antigenic carbohydrate. Further, the present invention relates to a method for screening a sterility or infertility treatment agent, or an anticonceptive using sialylated Tn sugar chains. A sialylated Tn antigen according to the present invention has a close relation with implantation of pregnancy. Therefore, a sialylated Tn antigen according to the present invention is capable of being used as a sterility treatment agent or an anticonceptive, and is used to measure pregnancy possibility or pregnancy efficiency. Further, a sialylated Tn antigen according to the present invention is capable of being used as a method for screening the sterility treatment agent or the anticonceptive.COPYRIGHT KIPO 2016본 발명은 시알화 Tn 당쇄 항원 또는 상기 항원을 활성화제를 유효성분으로 포함하는, 불임 또는 난임의 예방 또는 치료용 조성물에 관한 것이다. 또한, 본 발명은 시알화 Tn 당쇄 항원의 억제제 또는 상기 항원을 합성하는 효소의 발현 또는 활성 억제제를 포함하는, 피임용 약학 조성물에 관한 것이다. 또한, 본 발명은 시알화 Tn 당쇄 항원을 포함하는 임신 가능성 또는 임신 효율 측정용 마커 조성물에 관한 것이다. 또한, 본 발명은 시알화 Tn 당쇄를 이용하여 불임 또는 난임 치료제, 또는 피임제의 스크리닝 방법에 관한 것이다.
