An imaging system for imaging a portion(s) of an anatomical structure can be provided. For example, an x-ray source first arrangement can provide x-ray radiation, and a multi-hole collimator second arrangement can be provided in a path of the x-ray radiation, and can be configured to undersample the radiation beam which can be forwarded to the portion(s) of the anatomical structure. A third hardware arrangement can be configured to receive a further x-ray radiation from the portion(s) that can be based on the undersampled x-ray radiation.