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COMBINATION
专利权人:
GLAXOSMITHKLINE LLC
发明人:
RAKESH KUMAR,TONA M. GILMER
申请号:
BR112015008924
公开号:
BR112015008924A2
申请日:
2013.10.21
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
abstract the present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. in particular, the method relates to a cancer treatment method which includes administering n- {3-chloro-4 - [(3-fluorobenzyl) oxy] phenyl} -6- [5 - ({[2- (methanesulphonyl) ethyl] amino } methyl) -2-furyl] -4-quinazolinamine, or a pharmaceutically acceptable hydrate and / or salt thereof, and n - {(1s) -2-amino-1 - [(3,4-difluorophenyl) methyl] ethyl} -5-chloro-4- (4-chloro-1-methyl-1h-pyrazol-5-yl) -2-furancarboxamide, or a pharmaceutically acceptable salt thereof, for a human in need thereof. _____________________________________________________________ patent summary: "combination". The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. in particular, the method relates to a cancer treatment method which includes administration of n- {3-chloro-4 - [(3-fluorobenzyl) oxy] phenyl} -6- [5 - ({[2- (methanesulfonyl ) ethyl] amino} methyl) -2-furyl] -4-quinazolinamine or a hydrate and / or a pharmaceutically acceptable salt thereof and n - {(1s) -2-amino-1 - [(3,4-difluorophenyl) methyl] ethyl} -5-chloro-4- (4-chloro-1-methyl-1h-pyrazol-5-yl) -2-furancarboxamide or a pharmaceutically acceptable salt thereof to a human in need thereof.abstract the present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. in particular, the method relates to a cancer treatment method that includes administering n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine, or a pharmaceutically acceptable hydrate and/or salt thereof, and n-{(1s)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1h-pyrazol-5-yl)-2-furancarboxamide, or a pharmaceutically acceptable salt thereof, to a human in need thereof. __________________
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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