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SOLID PREPARATION
专利权人:
Youichi Takano
发明人:
Youichi Takano
申请号:
US13635082
公开号:
US20130017245A1
申请日:
2011.03.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a solid preparation having an easily controllable elution property of a drug, and a method for improving dissolution of a drug.A solid preparation 1 comprises a drug-containing unit 2 containing a drug, and a gel-forming layer 4 for covering the drug-containing unit 2 and forming a gel by water absorption, and optionally an intermediate layer 3 interposed between the drug-containing unit 2 and the gel-forming layer 4. The solid preparation 1 improves the elution property of the drug by incorporating an effervescent agent (e.g., sodium hydrogencarbonate) into the drug-containing unit 2 and/or the intermediate layer 3. The drug-containing unit 2 may contain a cationic or basic drug. The gel-forming layer 4 may contain an anionic or acidic polymer. The gel-forming layer 4 may be covered with a surface layer (anti-adhesive layer) 5.
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