PROCÉDÉ D'IDENTIFICATION DE MOTEURS DE FIBRILLATION CARDIAQUE ET/OU DE L'EMPREINTE D'ACTIVATIONS ROTATIVES À L'AIDE DE SIGNAUX OPTIQUES OU ÉLECTRIQUES UNIQUES SANS BESOIN D'UNE ACQUISITION SIMULTANÉE PANORAMIQUE
Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.);Fundación Para La Investigación Biomédica Del Hospital Clínico San Carlos
发明人:
申请号：
EP18382729.4
公开号：
EP3636147A1
申请日:
2018.10.11
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
This invention relates to ex vivo methods and uses, medical apparatus and related computer program and computer-readable medium for the determination of ablation sites for ablation treatments applied to cardiac tissue.In particular, it relates to an ex vivo (outside of the human or animal body) use of the instantaneous frequency modulation (iFM) signal calculated as the reciprocal of the intervals between consecutive cardiac activations during cardiac fibrillation, wherein said activations are obtained from i) a single or multiple electrical unipolar signals obtained via a single or multiple mapping electrodes, or ii) a single or multiple optical signals obtained via a single or multiple optical fibers, wherein preferably the spatial locations at the times of acquisition are used for constructing an electroanatomical map of the heart in a subject in need thereof, for detecting 'driver' or 'high-hierarchy' regions in the heart of a subject with cardiac fibrillation.
