Method for targeting a specific cell population using a cell-binding substance maytansinoid complex linked via a non-cleavable linker, the complex, and a method for producing the complex

• 收藏
• 分享

专利权人:

イミュノジェン・インコーポレーテッド

发明人:

スティーブス，リタ,ルッツ，ロバート,チャリ，ラヴィ,シェ，ホンシェン,コフトゥン，イェレナ,スティーブス,リタ,ルッツ,ロバート,チャリ,ラヴィ,シェ,ホンシェン,コフトゥン,イェレナ

申请号：

JP2011148625

公开号：

JP5718745B2

申请日:

2011.07.04

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The present invention discloses a method for targeting maytansinoids to a selected cell population, the method comprising contacting a cell population or tissue suspected of containing the selected cell population with a cell-binding agent maytansinoid conjugate, wherein one or more maytansinoids is covalently linked to the cell-binding agent via a noncleavable linker and the cell-binding agent binds to cells of the selected cell population.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/