The present invention relates to novel substituted piperidinyl-tetrahydroquinolines, to a method for the production thereof, to the use thereof for treating and/or preventing diseases, and to the use thereof for producing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for the promotion of wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular diseases of the heart, peripheral and cardiac vascular diseases, thromboembolic diseases and ischaemia, peripheral circulatory disorders, Raynaud's phenomenon, CREST syndrome, micro-circulation disorders, intermittent claudication, and peripheral and autonomic neuropathies.