The present invention provides a particle with a mean particle diameter of 5μm or less comprising pirfenidone and lipid, especially magnesium stearate, and a powder formulation comprising the particle and a carrier.本發明提供一種粒子,其含有吡非尼酮、以及脂質,特別是硬脂酸鎂,且平均粒徑為5μm以下;以及含有該粒子及載體的粉末製劑。