Methods and compositions using pde4 inhibitors for the treatment and management of autoimmune and inflammatory diseases

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专利权人:

CELGENE CORPORATION

发明人:

GANDHI ANITA,SCHAFER PETER,CAPONE LORI

申请号：

NZ61687512

公开号：

NZ616875A

申请日:

2012.04.27

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

The use of a first active agent for treating rheumatoid arthritis in a patient in need of such treatment, wherein the first active agent is of formula (I) or a pharmaceutically acceptable salt thereof, wherein said treating comprises administration of an additional active agent, and wherein the additional active agent is cyclosporine A. The compound of formula (I) is (S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide (Apremilast).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/