Subject of the invention is a method for the production of a carnitine granulate, comprising the steps of (a) providing an aqueous solution comprising at least 65% (w/w) carnitine, (b) providing a particulate carrier comprising silica, the carrier having an average particle size of more than 150μm, and (c) mixing the aqueous solution and the carrier.Another subject of the invention is a carnitine granulate.本發明之主題為一種製造肉毒鹼顆粒之方法,其包含以下步驟:(a)提供包含至少65%(w/w)肉毒鹼之水溶液,(b)提供包含二氧化矽之微粒狀載劑,該載劑之平均粒度大於150μm,及(c)將該水溶液與該載劑混合。本發明之另一主題為一種肉毒鹼顆粒。