Metal complexes with bisphosphonate or pyrophosphate useful as imaging agents

• 收藏
• 分享

专利权人:

Duke University

发明人:

Lascola, Christopher David

申请号：

AU2016252864

公开号：

AU2016252864A1

申请日:

2016.04.22

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

Provided herein are magnetic resonance imaging (MRI) contrast agents comprising a compound having a structure represented by: Y - X - Z, wherein, X is: Fe(III) or Mn(II), and Y and Z are each independently selected from pyrophosphate and bisphosphonate (e.g., 1-hydroxybisphosphonate), or a pharmaceutically acceptable hydrate and/or salt thereof. Methods of use of the MRI contrast agent are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/