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immediate release coating composition with improved moisture barrier properties, aqueous suspension, coated oral substrate, oral dosage form and method of preparation thereof
专利权人:
BPSI HOLDINGS; LLC
发明人:
JASON TECKOE,THOMAS P. FARREL
申请号:
BRPI1007725
公开号:
BRPI1007725A2
申请日:
2010.04.28
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention is directed to immediate release film coating systems for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which have improved moisture barrier properties. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the moisture barrier film coating is prepared as a dry powder mixture containing polyvinyl alcohol, a polymer with pH dependent solubility, a plasticizer, a glidant, and, optionally, a detackifier, an alkalizing agent and a pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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