YANAGISAWA, KATSUHIKO;MEDICAL & BIOLOGICAL LABORATORIES CO., LTD.;JAPAN AS REPRESENTED BY THE DIRECTOR OF CHUBU NATIONAL HOSPITAL
发明人:
申请号：
EP02755765.1
公开号：
EP1420032B2
申请日:
2002.08.01
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
It is intended to provide an antibody efficacious in diagnosing, preventing or treating Alzheimer's disease, DNA encoding the antibody, a method of screening a drug and drugs. The amino acid sequence and the gene sequence of the variable region of an antibody, which specifically recognizes a GM1 ganglioside-bound amyloid beta -protein occurring in the early stage of beta -amyloid fibril formation, are determined. Based on the data of the amino acid sequence and the gene sequence thus obtained, an antibody is designed.
