LIU, ZHI,ZHONGHUA, HU,FANSLOW, WILLIAM C.,YAN, WEI
申请号:
CA3042249
公开号:
CA3042249A1
申请日:
2017.11.06
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Anti-CTLA4 antibodies, anti-PD1 antibodies, mixtures thereof, polynucleotides encoding such antibodies or mixtures, optionally carried on vectors, and methods of treatment utilizing such antibodies, mixtures, polynucleotides, or vectors are described herein. The anti-CTLA4 and anti-PD1 antibodies have particular sequences and properties. The methods of treatment include uses in treatment of cancer, infections, and immunodeficiency disorders.