PROCESS FOR THE PRODUCTION OF A PEMETREXED SALT

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专利权人:

LTD.;SCINOPHARM TAIWAN

发明人:

CHEN, SHANGHONG,LIN, HUANGHSIUNG

申请号：

EP11862192

公开号：

EP2688888A4

申请日:

2011.03.25

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

A process of making a pemetrexed salt comprising: a) reacting a compound of formula II or an acid salt thereof, wherein each of R1 and R2 is independently a C1-C6 alkyl group, with an aqueous basic solution at a temperature of no more than 10°C to obtain a first mixture comprising the pemetrexed salt； b) isolating the pemextrexed salt from the first mixture.

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中国工程科技知识中心

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