[Object] To provide a pharmaceutical composition which is excellent as a medicament for prevention or treatment of diseases relating to immune action such as autoimmune diseases.[Means for Solution]A pharmaceutical composition comprising1 or 2 or more selected from PPAR regulators and1 or 2 or more selected from the group consisting of amino alcohol derivatives of the general formula (I):[whereinR1 and R2 are the same or different, and each represents a hydrogen atom or the like R3 represents a C1-C6 alkyl group or a hydroxymethyl group R4 represents a hydrogen atom, a C1-C6 alkyl group or the like R5 represents a phenyl group substituted with 1 to 3 substituents selected from the group consisting of a hydrogen atom, a halogen atom, a cyano group, a C1-C6 alkyl group or the like X represents a vinylene group (CH=CH group), an oxygen atom or the like Y represents a single bond, an oxygen atom or the like Z represents a single bond, a C1-C8 alkylene group or the like n represents an integer of 2 or 3] andpharmacologically acceptable salt thereof.