PROBLEM TO BE SOLVED: To provide an aqueous solid ointment excellent in long-term storage stability and storage stability at low temperatures, which can prevent crystal precipitation of a fatty acid salt which easily occurs by long-term storage or low temperature storage and the deterioration in appearance, changes in efficacy or safety or the like caused by the crystal precipitation.SOLUTION: There is provided an aqueous solid ointment excellent in long-term storage stability and storage stability at low temperatures, which can prevent crystal precipitation of a fatty acid salt which causes deterioration in appearance, changes in efficacy or safety or the like by blending a sucrose fatty acid ester in an aqueous solid ointment comprising an active ingredient, a fatty acid salt and a lower alcohol.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】長期間の保存や低温での保存により容易に生じる脂肪酸塩の結晶析出およびそれに伴い引き起こされる外観の悪化、有効性や安全性の変化などを防止することができ、長期間の保存安定性および低温での保存安定性に優れた水性固形軟膏を提供すること。【解決手段】有効成分、脂肪酸塩および低級アルコールからなる水性固形軟膏中にショ糖脂肪酸エステルを配合することで、外観の悪化、有効性や安全性の変化などを引き起こす脂肪酸塩の結晶析出を抑制でき、長期間の保存安定性および低温での保存安定性に優れた水性固形軟膏である。【選択図】なし
