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Nucleic acid delivery system comprising conjugates of PEI and hyaluronic acid
专利权人:
Yu-Kyoung Oh
发明人:
Yu-Kyoung Oh,Hyun-Gu Kang,Ji-Seok Kim,Jiang Ge,Ki-Su Kim,Ki-Tae Park,Su-Eun Han,Ga-Yong Shim,Ii-Hwan Cho,Sei-Kwang Hahn
申请号:
US12733061
公开号:
US08318856B2
申请日:
2008.04.04
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a delivery system for nucleic acid using a cationic polymer conjugate, and more specifically relates to a delivery system for nucleic acid comprising a cationic polymer conjugate prepared by conjugating hyaluronic acid or its derivative and polyethyleneimine, and a composition of delivering a nucleic acid into mammalian cell comprising a complex of the nucleic acid and a cationic polymer conjugate with electrostatic binding.
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