Gregory, Philip D.,Miller, Jeffrey C.,Paschon, David,Rebar, Edward J.,Tan, Siyuan,Urnov, Fyodor,Zhang, Lei
申请号:
AU2011256838
公开号:
AU2011256838A1
申请日:
2011.05.17
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.