University of Medicine and Dentistry of New Jersey
发明人:
Lin, Peihui,Ma, Jianjie,Weisleder, Noah,Zhu, Hua
申请号:
AU2010254820
公开号:
AU2010254820B2
申请日:
2010.06.04
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Disclosed herein are compositions and methods for treatment of muscle dysfunction, including diabetes. In addition, the invention relates to therapeutic compositions comprising nucleotides and/or polypeptides of the invention in combination with a pharmaceutically acceptable carrier, wherein the composition facilitates the treatment of skeletal musle disorders. Moreover, the invention relates to the treatment and/or prevention of pathological conditions associated with altered intracellular Ca2+ reulgation and disrupted membrane structure that occurs when the expression levels of MG29 are reduced.