The present invention (for example, non-enzymatic glycation end-product or disease state) tissue state of the object relates to a method for determining a measure of the. Tissue is part of the object after receiving the light by the excitation light, due to the fluorescence of the compound having a structure in response to the excitation light is detected the light emitted by the tissue. The detected light may be coupled to a model associating the measurement of tissue fluorescence and conditions to measure the tissue condition. The invention may include the detection, scanning combinations thereof (detection light emitted from the plurality of wavelength), and the detection wavelength of the single wavelength of the excitation light, the excitation light scanning (shining a tissue at a plurality of wavelengths), a single wavelength is. In addition, the present invention may include a compensation technique to reduce error judgment by the detection of the light other than the fluorescence of the compound within the tissue. For example, the reflectance of the tissue can cause errors unless suitable compensation is made. The present invention also may include various ways to produce a variety of models, and these models relating to the fluorescence for the measurement of tissue status. Other biological information can be used in combination with the fluorescence to aid in the determination of the measured tissue condition. The present invention also includes a suitable light source, detector and a model to be used in connection with the measurement of the detected fluorescence and tissue state suitable device for performing the method, including (for example, provided on the computer).Fluorescence, skin, saccharification end products, AGE, Diabetes본 발명은 개체의 조직 상태(예를 들어, 비효소적 당화 최종산물 또는 질병 상태)의 측정을 판정하는 방법에 관한 것이다. 개체의 조직 부분은 여기광에 의해 빛을 받은 후, 여기광에 반응하는 조직을 갖는 화합물의 형광으로 인해 조직에 의해 방출된 빛이 검출된다. 상기 검출된 빛은 조직 상태를 측정하기 위하여 조직 상태의 측정과 형광을 연관짓는 모델에 결합될 수 있다. 본 발명은 단
