The present invention relates to a brace (420) for use with an ankle/foot having first and second opposing sides (410,412), comprising a plurality of lace guide pairs (450), with opposing guides positioned on the opposing sides, a lace (423) extending back and forth between the opposed guides, a rotatable tightening mechanism (425) configured to apply tension on the lace, thereby advancing the opposed guides towards each other, and a tongue (415) configured to be positioned between the first and second sides when the brace is closed, wherein all of the guides on the first side of the brace permit release of the lace from the first side of the brace.