Compositions and methods for repelling arthropods. The compositions include a carrier and an arthropod repelling compound which can be a compound discovered by a novel and complex cheminformatic process to demonstrate repellency behavior across a broad spectrum of arthropods. The compound can be a thiane compound a pyrrolidone compound a cyclohexadiene compound a cyclohexenone compound a cyclohexene compound a furanone compound a pyran compound a tetrahydropyran compound a thiazolidine compound a thiazoline compound a dihydrothiophene compound a dithiolane compound a dithiane compound an epoxide compound an oxathiane compound a cyclopentene compound a cyclohexane compound a quinoline compound an oxazoline compound a tetrahydropyridine compound and an imidazolidinone compound or a combination thereof.
