The protection and accommodation system is suitable in particular for a device (C) for delivering a treatment to a patient, for instance a drug by intravenous way. The system includes: a support structure arranged to be attached in a removable manner to the patients body, and a retaining structure associated with the support structure and Including a deformable material arranged to be deformed by a compression performed by an operator which pushes a fixing portion (W) of the delivery device (C) against the deformable material, and arranged for embedding and retaining the fixing portion (W) by at least partial, elastic return performed by the deformable material after the compression performed by the operator.