Direct selection of cells expressing high levels of heteromeric proteins using glutamine synthetase intragenic complementation vectors

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专利权人:

Amgen Inc.

发明人:

Ketchem, Randal R.,McGrew, Jeffrey T.,Fomina Yadlin, Dina A.,Munro, Trent P.,Agrawal, Neeraj Jagdish,Daris, Kristine M.

申请号：

AU20170263454

公开号：

AU2017263454(A1)

申请日:

2017.05.11

申请国别(地区):

澳大利亚

年份:

2018

代理人:

摘要：

This invention relates to the general field of recombinant expression of polypeptides in animal cell culture. More specifically, the invention concerns improved selection of cells transfected with recombinantly engineered vectors designed to express polypeptides, in particular heteromultimeric polypeptides.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/