FXA inhibitors with cyclic amidoxime or cyclic amidrazone as P4 subunit, processes for their preparations, and pharmaceutical compositions and derivatives thereof
Sung Ho Woo;Yong Zu Kim;Hyang Sook Lee;Sang Hui Jo;Yeon Ok Kim;Hee Sock Park;Ho Young Song;Sang Eun Chae;Young Lag Cho;Ju Hyun Park;Dae Yon Lee;Sung Yoon Baek;Tae Kyo Park
发明人:
Ho Young Song,Young Lag Cho,Dae Yon Lee,Hee Sock Park,Sung Yoon Baek,Sang Eun Chae,Sang Hui Jo,Yeon Ok Kim,Hyang Sook Lee,Ju Hyun Park,Tae Kyo Park,Sung Ho Woo,Yong Zu Kim
申请号：
US13002271
公开号：
US08178525B2
申请日:
2009.06.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are novel oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group, pharmaceutically acceptable salts thereof, methods for preparing the same and pharmaceutical compositions containing the same. The oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group or the pharmaceutically acceptable salts thereof can be effectively used for the treatment of thromboembolism and tumor as an anticoagulant based on the inhibition of factor Xa.
