Therapeutic compositions containing fusion proteins (FPs) including elastin-likepeptides (ELPs) and peptide active therapeutic agents, and methods of makingand using such compositions and fusion proteins. Therapeutic compositionsof such type enable improved efficacy of the peptide active therapeutic agentto be achieved, in relation to the peptide active therapeutic agent alone. Enhancedefficacy of the peptide active therapeutic agent in the therapeutic compositionmay include improved solubility, bioavailability, bio-unavailability, half-life,etc., as compared to corresponding compositions containing the same peptideactive therapeutic agent without associated ELPs.
