NOUVELLE ISOFORME DE LA KINASE DU LYMPHOME ANAPLASIQUE ET SES UTILISATIONS

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专利权人:

MEMORIAL SLOAN-KETTERING CANCER CENTER

发明人:

CHI, PING,WIESNER, THOMAS,CHEN, YU

申请号：

CA2945324

公开号：

CA2945324A1

申请日:

2015.04.10

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The present invention relates to a Truncated isoform of Anaplastic Lymphoma Kinase ("TALK"). Expression of this isoform is associated with malignancy and with responsiveness to ALK inhibitors. Detection of the isoform may be used in diagnostic and therapeutic methods. Because it arises as a result of variant transcription rather than genetic rearrangement, its presence would be undetected by genomic testing.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/