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Means and methods using paramagnetic agents for in vitro diagnostic applications
专利权人:
发明人:
Uri Rapoport,Camila Cavallotti,Simonetta Geninatti Crich
申请号:
US14090298
公开号:
US09482643B2
申请日:
2013.11.26
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A method of detecting a target biochemical molecular species or at least one property correlated with the occurrence of the biochemical molecular species in a sample whose main component is water. The method includes: obtaining a sample whose main component is water providing Functionalized Paramagnetic Particles (FPP) including a paramagnetic core and a moiety configured to interact with the target biochemical molecular species or with molecules collectively reporting on a property of the target biochemical molecular species contacting the FPP with the sample exposing the sample to an applied magnetic field measuring a change in a nuclear relaxation property of the sample and correlating the change to the presence of the biochemical molecular species in the sample or to at least one property correlated with the occurrence of the biochemical molecular species in the sample.
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