SHANGHAI TISSUE ENGINEERING LIFE SCIENCE CO. LTD.;SHANGHAI 9TH PEOPLE'S HOSPITAL, SHANGHAI JIAOTONGUNIVERSITY SCHOOL OF MEDICINE
发明人:
CAO, YILIN,LIU, WEI,XU, FENG,DENG, DAN,LI, HONG
申请号：
EP08715302
公开号：
EP2172231A4
申请日:
2008.03.24
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
The invention discloses a tissue engineering graft, comprising:(a) pharmaceutically-acceptable biodegradable material； and (b) seed cells, which can be inoculated on the described biodegradable material and are selected from:(i) fibroblasts； (ii) adipose derived cells, or (iii) mixture of dermal fibroblasts and ASCs according to the ratio of 1:10000-10000:1. The graft can be prepared by mixing of seed cell and pharmaceutically-acceptable biodegradable material, obtaining a construct of seed cells and pharmaceutically-acceptable biodegradable material, then culturing the construct in a bioreactor in vitro. The graft can be used for repairing the defect of tendon tissues.
