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1,6-disubstituted indole compounds as protein kinase inhibitors
专利权人:
Tae Bo Sim
发明人:
Tae Bo Sim,Young Jin Ham,Kyung Ho Yoo,Chang Hyun Oh,Jung Mi Hah,Hwan Geun Choi,Hwan Kim,Eun Jin Jun
申请号:
US13504355
公开号:
US08765749B2
申请日:
2010.10.20
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are a 1,6-substituted indole compound having a protein kinase inhibition activity, a pharmaceutically acceptable salt, and a pharmaceutical composition for prevention and treatment of cancers caused by abnormal cell growth comprising the compound as an effective ingredient.Since the novel indole compound exhibits superior inhibition activity against various protein kinases involved in growth factor signal transduction, it is useful as an agent for preventing or treating cancers caused by abnormal cell growth.
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