The present invention provides an antibody which has an activity of binding specifically to human membrane-type ADAM28 at an epitope present in a domain lying between amino acid residue 524 and amino acid residue 659 in the amino acid sequence represented by SEQ ID NO: 2. The present invention also provides a drug delivery medium for delivering a drug to a cell or tissue in which human membrane-type ADAM28 can be expressed, said drug delivery medium comprising the antibody.