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IDO INHIBITORS
专利权人:
发明人:
MAUTINO MARIO,JAIPURI FIROZ,MARCINOWICZ FLICK AGNIESZKA,KESHARWANI TANAY,WALDO JESSE,COLLIER STEVEN JAMES
申请号:
IN201738035639
公开号:
IN201738035639A
申请日:
2017.10.07
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
A compound of the formula, or a pharmaceutically acceptable salt thereof, wherein L1 is –C2-C6alkyl- X is =0 or =S ring D is an aryl or heteroaryl group, each optionally substituted with one to four R groups R1 is – L2-R2, wherein L2 is is –C2-C6alkyl- and R2 is (i) hydrogen (ii) aryl optionally substituted with one to four R groups or (iii) heteroaryl optionally substituted with one to four R groups and each R is independently halogen, cyano, nitro, C1-C6alkyl, C2-C6alkenyl, C2-C6alkynyl, -OR3, -SR3, -N(R3)2, - OC(O)R3, -C(O)OR3, -C(O)N(R3)2 – N(R3)C(O)R3, -S(O)R3, or –S(O)2R3, wherein each R is independently hydrogen or C1- C6alkyl provided that when ring D is an aryl or unsubstituted indol-3-yl, benzofuran-3-yl, or benzothien-3-yl group, and L1 is –C2- C3alkyl-, then (a) R2 is not hydrogen.
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