Alexandra Jane Spencer,Matthew Guy Cottingham,Adrian Vivian Sinton Hill,Fergal Hill
申请号：
US13501756
公开号：
US20120282290A1
申请日:
2010.10.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
There is provided a fusion protein or a polynucleotide sequence encoding said fusion protein that comprises first and second domains, wherein the first domain of the fusion protein comprises an amino acid sequence having at least 70% sequence identity to the amino acid sequence of SEQ ID NO: 1, or a fragment thereof comprising at least 20 consecutive amino acids thereof and wherein the second domain of the fusion protein comprises a mycobacterial antigen or an antigenic fragment thereof. Also provided are corresponding therapeutic uses thereof for the protection of primates against mycobacterial infections.
